James Fadiman, an early psychedelic researcher, and co-author Jordan Gruber’s MICRODOSING FOR HEALTH, HEALING AND ENHANCED PERFORMANCE is the first comprehensive book on microdosing, using new research and extensive reports from individuals to describe the possibilities of the practice.
MICRODOSING FOR HEALTH, HEALING, AND ENHANCED PERFORMANCE
by James Fadiman & Jordan Gruber
St. Martin’s Press, February 2025
(via Levine Greenberg Rostan Literary Agency)
Microdosing is proving to be a safe and powerful approach to a wide range of health conditions and enhanced performance. Partly responsible for modern microdosing’s development and current popularity, the authors answer hundreds of questions, blending extensive research with detailed personal accounts from contributors worldwide. The book also contains wide-ranging microdosing history, research, and science.
People have microdosed successfully:
· to alleviate symptoms of depression, ADHD, chronic pain, and long COVID
· for enhanced focus, mental acuity, and physical abilities (including sports)
· to help taper off pharmaceuticals, especially antidepressants and stimulants
· to improve food habits, sleep, and relationships
· to become more aware of personal habit patterns, others’ feelings, and natural surroundings
· to reduce stress and anxiety
· to help over 30 specific health concerns
This book does not provide medical or legal advice. Readers should speak to their doctor before engaging in any course of microdosing.
James Fadiman was introduced to psychedelics by Ram Dass six decades ago. Fifteen years ago, he began compiling thousands of stories from microdosers who used his protocol and now has the largest qualitative database on microdosing in the world. He’s been the godfather to anyone interested in the field, from Michael Pollan to novelist Ayelet Waldman.
Jordan Gruber has authored, coauthored, or edited many nonfiction books, from forensics and finances to health and psychology, including, with Fadiman, Your Symphony of Selves.


In this relatable story, a young girl is trying to fall asleep but can’t because of all her worries and what-ifs. Her mother gives her some excellent advice—that it’s understandable that thoughts would want to stick around in her beautiful mind, but that she’ll want to leave room for good thoughts, too—that helps her envision happy, calming moments that “nest” in her mind.
Many of us experience periods in our lives when something feels “off”: when we struggle to find joy in happy moments, and take little pleasure in things we used to enjoy. We might be motivated and productive at work, pulling our weight at home, and conducting a normal social life—but behind that façade we are barely surviving, and certainly not thriving.